Beschreibung
Invited Lecture - Strength training during chemotherapy of breast cancer patients - the Cologne study resultsKnicker, A.1, Baumann, F.1, Bloch, W.1, Strüder, H.1, Rojas, S.1, Leskaroski, A.1, Drosselmeier, N.1, Müller, S.1, Schroer, K.1, Harbeck, N.2, Mallmann, P.2, Schneider, J.2, Krakowski – Roosen, H. 3
1German Sport University (Cologne, Germany), 2University Hospital of Cologne (Cologne, Germany), 3 German Cancer Research Center (Heidelberg, Germany
Introduction
Cancer related fatigue (CRF) is one of the most stressful symptoms for women after breastcancer surgery. The causes of CRF remain unclear and symptoms are accompanied by mental impairment, a general lack of drive and rapid exhaustion after physical activity and can last for even years after surgery. CRF is experienced as a multidimensional subjective experience in nearly all cancer patients. During chemotherapy between up to 96% of the patients suffer from fatigue symptoms.
Methods
Different groups of breast cancer patients have taken part in progressive strength training programs during their chemo therapy. The general endpoint variables of the studies have been fatigue aspects and quality of life with special focus in some of the studies on cognitive abilities. Strength gains for selected muscle groups have been registered on an isokinetic dynamometer (IsoMed2000) in isometric and isokinetic test modes. A group of healthy women undergoing identical training regimes served as a control for the estimation of strength developments in the cancer groups.
Results
Current research and own pilot studies indicate, that especially progressive, hypertrophic strength training has positive effects on the physical, psychological and cognitive state of the patient. Strength training leads to adaptations on metabolic, cellular and neuronal levels. The strength level of breast cancer patients can be raised significantly during chemotherapie (12 weeks exercise period).
Discussion
Compared to age matched healthy controls the strength gain of breast cancer patients is considerably low and cannot uniquivocally be attributed to hypertrophic adaptations within the muscle. However the loss of strength abilities of control cancer patients without strength training was of cachectic dimension whereas the strength training groups could at least retain if not improve their stregth level. They also reported only mild side effects and no nausea, no vomiting, no loss of apetite, a weight gain instead of weight loss, short lasting fatigue which can mainly be atributed to psychosocial fascilitation.
References
1. Cramp F, Daniel J. Exercise for the management of cancer-related fatigue in adults. Cochrane Database Syst Rev. 2008 Apr 16;(2)
2. Knicker, A. J., Müller, S., Baumann, F., Krakowski-Roosen, H., Schneider, J., Strüder, H.K. Strength training accompanying chemotherapy after lumpectomy. 2008, 13th Annual Congress ECSS, Estoril, Portugal
3. Meyers CA. Neurocognitive dysfunction in cancer patients. Oncology 14: 75-79 (2000)
4. Ryan JL, Carroll JK, Ryan EP, Mustian KM, Fiscella K, Morrow GR. Mechanisms of cancer-related fatigue. Oncologist. 2007;12 Suppl 1:22-34
| Zeitraum | 17.10.2009 |
|---|---|
| Veranstaltungstyp | Sonstiges |
| Sponsor | |
| Ort | Antalya, TürkeiAuf Karte anzeigen |
| Bekanntheitsgrad | International |