TY - JOUR
T1 - Adipokine-Myokine-Hepatokine Compartment-System in mothers and children: an explorative study
AU - Deibert, Clara
AU - Ferrari, Nina
AU - Flöck, A.
AU - Merz, W.M.
AU - Gembruch, U.
AU - Lehmacher, Walter
AU - Ehrhardt, Christina
AU - Graf, Christine
PY - 2016/2/12
Y1 - 2016/2/12
N2 - Maternal lifestyle during pregnancy has an effect of gestational development and neonatal outcome. Overweight gravidas and gravidas with excessive weight gain have an increased risk of gestational complications and neonatal metabolic disorder. The underlying mechanisms are still under discussion, but the hormonally active fat mass and its biomarkers, adipocytokines, may play a key role by potentially having a direct impact on the metabolic homeostasis of the system in concert with other biomarkers like hepatokines and myokines. Up to now little is known in terms of lifestyle habits and their effect on this complex model on maternal and fetal outcome. Therefore, we aim to investigate the influence of maternal lifestyle clusters during pregnancy on the maternal and fetal biomarkers of compartments, specifically those implying maternal fat and muscle mass, maternal liver and the placenta and who are associated with maternal body composition and birth weight.
AB - Maternal lifestyle during pregnancy has an effect of gestational development and neonatal outcome. Overweight gravidas and gravidas with excessive weight gain have an increased risk of gestational complications and neonatal metabolic disorder. The underlying mechanisms are still under discussion, but the hormonally active fat mass and its biomarkers, adipocytokines, may play a key role by potentially having a direct impact on the metabolic homeostasis of the system in concert with other biomarkers like hepatokines and myokines. Up to now little is known in terms of lifestyle habits and their effect on this complex model on maternal and fetal outcome. Therefore, we aim to investigate the influence of maternal lifestyle clusters during pregnancy on the maternal and fetal biomarkers of compartments, specifically those implying maternal fat and muscle mass, maternal liver and the placenta and who are associated with maternal body composition and birth weight.
U2 - 10.1016/j.conctc.2016.02.002
DO - 10.1016/j.conctc.2016.02.002
M3 - Journal articles
VL - 3
SP - 1
EP - 5
JO - Contemporary Clinical Trials Communications
JF - Contemporary Clinical Trials Communications
ER -