Endothelial nitric oxide synthase phosphorylated at Ser116 is localized in nerve fibers of the rat glandulae palatinae

Yüksel Korkmaz; Wilhelm Bloch; Klaus Addicks; Michael A Baumann; Wolfgang H-M Raab

doi:10.1016/j.neulet.2004.03.045

Endothelial nitric oxide synthase phosphorylated at Ser116 is localized in nerve fibers of the rat glandulae palatinae

Yüksel Korkmaz, Wilhelm Bloch, Klaus Addicks, Michael A Baumann, Wolfgang H-M Raab

Abteilung Molekulare und zelluläre Sportmedizin

Heinrich-Heine-Universität Düsseldorf

Publikation: Beitrag in Fachzeitschrift › Zeitschriftenaufsätze › Forschung

Abstract

It is known that total endothelial nitric oxide synthase (eNOS) is localized in peripheral nerve fibers, but the existence of the phosphorylation site/s of eNOS in peripheral nerve fibers is unknown. In the perfusion-fixed and decalcified sections of rat palates, eNOS and eNOS phosphorylated at Ser(116) were identified in the nerve fibers of the glandulae palatinae. The localization of eNOS phosphorylated at Ser(1177) and Thr(495) in nerve fibers was undetectable. It is concluded that eNOS is phosphorylated at Ser(116) in nerve fibers of the glandulae palatinae under basal conditions. The basal Ser(1177) and Thr(495) phosphorylation of eNOS are missing in nerve fibers of the glandulae palatinae.

Originalsprache	Englisch
Zeitschrift	Neuroscience letters
Jahrgang	363
Ausgabenummer	1
Seiten (von - bis)	54-57
Seitenumfang	4
ISSN	0304-3940
DOIs	https://doi.org/10.1016/j.neulet.2004.03.045
Publikationsstatus	Veröffentlicht - 03.06.2004

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10.1016/j.neulet.2004.03.045

Zitation

@article{a158f06e42c1408e8ff112887cd7e519,

title = "Endothelial nitric oxide synthase phosphorylated at Ser116 is localized in nerve fibers of the rat glandulae palatinae",

abstract = "It is known that total endothelial nitric oxide synthase (eNOS) is localized in peripheral nerve fibers, but the existence of the phosphorylation site/s of eNOS in peripheral nerve fibers is unknown. In the perfusion-fixed and decalcified sections of rat palates, eNOS and eNOS phosphorylated at Ser(116) were identified in the nerve fibers of the glandulae palatinae. The localization of eNOS phosphorylated at Ser(1177) and Thr(495) in nerve fibers was undetectable. It is concluded that eNOS is phosphorylated at Ser(116) in nerve fibers of the glandulae palatinae under basal conditions. The basal Ser(1177) and Thr(495) phosphorylation of eNOS are missing in nerve fibers of the glandulae palatinae.",

keywords = "Animals, Immunohistochemistry, Male, Nerve Fibers, Nitric Oxide Synthase, Nitric Oxide Synthase Type III, Palate, Phosphorylation, Rats, Rats, Wistar, Serine",

author = "Y{\"u}ksel Korkmaz and Wilhelm Bloch and Klaus Addicks and Baumann, {Michael A} and Raab, {Wolfgang H-M}",

year = "2004",

month = jun,

day = "3",

doi = "10.1016/j.neulet.2004.03.045",

language = "English",

volume = "363",

pages = "54--57",

journal = "Neuroscience letters",

issn = "0304-3940",

publisher = "Elsevier",

number = "1",

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TY - JOUR

T1 - Endothelial nitric oxide synthase phosphorylated at Ser116 is localized in nerve fibers of the rat glandulae palatinae

AU - Korkmaz, Yüksel

AU - Bloch, Wilhelm

AU - Addicks, Klaus

AU - Baumann, Michael A

AU - Raab, Wolfgang H-M

PY - 2004/6/3

Y1 - 2004/6/3

N2 - It is known that total endothelial nitric oxide synthase (eNOS) is localized in peripheral nerve fibers, but the existence of the phosphorylation site/s of eNOS in peripheral nerve fibers is unknown. In the perfusion-fixed and decalcified sections of rat palates, eNOS and eNOS phosphorylated at Ser(116) were identified in the nerve fibers of the glandulae palatinae. The localization of eNOS phosphorylated at Ser(1177) and Thr(495) in nerve fibers was undetectable. It is concluded that eNOS is phosphorylated at Ser(116) in nerve fibers of the glandulae palatinae under basal conditions. The basal Ser(1177) and Thr(495) phosphorylation of eNOS are missing in nerve fibers of the glandulae palatinae.

AB - It is known that total endothelial nitric oxide synthase (eNOS) is localized in peripheral nerve fibers, but the existence of the phosphorylation site/s of eNOS in peripheral nerve fibers is unknown. In the perfusion-fixed and decalcified sections of rat palates, eNOS and eNOS phosphorylated at Ser(116) were identified in the nerve fibers of the glandulae palatinae. The localization of eNOS phosphorylated at Ser(1177) and Thr(495) in nerve fibers was undetectable. It is concluded that eNOS is phosphorylated at Ser(116) in nerve fibers of the glandulae palatinae under basal conditions. The basal Ser(1177) and Thr(495) phosphorylation of eNOS are missing in nerve fibers of the glandulae palatinae.

KW - Animals

KW - Immunohistochemistry

KW - Male

KW - Nerve Fibers

KW - Nitric Oxide Synthase

KW - Nitric Oxide Synthase Type III

KW - Palate

KW - Phosphorylation

KW - Rats

KW - Rats, Wistar

KW - Serine

U2 - 10.1016/j.neulet.2004.03.045

DO - 10.1016/j.neulet.2004.03.045

M3 - Journal articles

C2 - 15157995

SN - 0304-3940

VL - 363

SP - 54

EP - 57

JO - Neuroscience letters

JF - Neuroscience letters

IS - 1

ER -

Endothelial nitric oxide synthase phosphorylated at Ser116 is localized in nerve fibers of the rat glandulae palatinae

Abstract

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