High amounts of 17-methylated anabolic-androgenic steroids in effervescent tablets on the dietary supplement market

Maria Kristina Parr, Hans Geyer, Bernhard Hoffmann, Karsten Köhler, Ute Mareck, Wilhelm Schänzer

Publikation: Beitrag in FachzeitschriftZeitschriftenaufsätzeForschungBegutachtung

Abstract

In numerous studies it has been demonstrated that several nutritional supplements contain prohormones not declared on the label. In the current study two products (effervescent tablets) containing high amounts of the 17-methylated anabolic androgenic steroids metandienone (product 1: 16.8 mg/tablet) and stanozolol (product 2: 14.5 mg/tablet) were identified. Additionally in both products norandrostenedione was detected, in product 2 with minor amounts of several other steroids. The substances identified can cause enormous health risks. In addition, the use of the analyzed tablets can lead to positive doping results for metabolites of the respective steroids in sports. This study again shows the insufficient surveillance of the production and trade of dietary supplements. Consumers should be aware of the enormous health and doping risks connected with the use of such products. For GC-MS identification of the analytes the trimethylsilyl derivatives of the steroids and the mixed N-t-butyldimethylsilyl,O-trimethylsilyl derivatives were used. The quantitation of metandienone, norandrostenedione, and stanozolol was performed using HPLC-DAD.

OriginalspracheEnglisch
ZeitschriftBiomedical chromatography : BMC
Jahrgang21
Ausgabenummer2
Seiten (von - bis)164-168
Seitenumfang5
ISSN0269-3879
DOIs
PublikationsstatusVeröffentlicht - 01.02.2007

Fingerprint

Untersuchen Sie die Forschungsthemen von „High amounts of 17-methylated anabolic-androgenic steroids in effervescent tablets on the dietary supplement market“. Zusammen bilden sie einen einzigartigen Fingerprint.

Zitation