Quantitative T2* assessment of knee joint cartilage after running a marathon

Tobias Hesper; Falk R Miese; Harish S Hosalkar; Michael Behringer; Christoph Zilkens; Gerald Antoch; Rüdiger Krauspe; Bernd Bittersohl

doi:10.1016/j.ejrad.2014.11.021

Quantitative T2* assessment of knee joint cartilage after running a marathon

Tobias Hesper, Falk R Miese, Harish S Hosalkar, Michael Behringer, Christoph Zilkens, Gerald Antoch, Rüdiger Krauspe, Bernd Bittersohl

Publikation: Beitrag in Fachzeitschrift › Zeitschriftenaufsätze › Forschung › Begutachtung

Abstract

OBJECTIVE: To study the effect of repetitive joint loading on the T2(*) assessment of knee joint cartilage.

MATERIALS AND METHODS: T2(*) mapping was performed in 10 non-professional marathon runners (mean age: 28.7±3.97 years) with no morphologically evident cartilage damage within 48h prior to and following the marathon and after a period of approximately four weeks. Bulk and zonal T2(*) values at the medial and lateral tibiofemoral compartment and the patellofemoral compartment were assessed by means of region of interest analysis. Pre- and post-marathon values were compared.

RESULTS: There was a small increase in the T2(*) after running the marathon (30.47±5.16ms versus 29.84±4.97ms, P<0.05) while the T2(*) values before the marathon and those after the period of convalescence were similar (29.84±4.97ms versus 29.81±5.17ms, P=0.855). Regional analyses revealed lower T2(*) values in the medial tibial plateau (P<0.001).

CONCLUSIONS: It appears that repetitive joint loading has a transient influence on the T2(*) values. However, this effect is small and probably not clinically relevant. The low T2(*) values in the medial tibial plateau may be related to functional demand or early cartilage degeneration.

Originalsprache	Englisch
Zeitschrift	European journal of radiology
Jahrgang	84
Ausgabenummer	2
Seiten (von - bis)	284-9
Seitenumfang	6
ISSN	0720-048X
DOIs	https://doi.org/10.1016/j.ejrad.2014.11.021
Publikationsstatus	Veröffentlicht - 01.02.2015

Zugriff auf Dokument

10.1016/j.ejrad.2014.11.021

Zitation

@article{aa57ce072b0748b5825758ecca6a9b70,

title = "Quantitative T2* assessment of knee joint cartilage after running a marathon",

abstract = "OBJECTIVE: To study the effect of repetitive joint loading on the T2(*) assessment of knee joint cartilage.MATERIALS AND METHODS: T2(*) mapping was performed in 10 non-professional marathon runners (mean age: 28.7±3.97 years) with no morphologically evident cartilage damage within 48h prior to and following the marathon and after a period of approximately four weeks. Bulk and zonal T2(*) values at the medial and lateral tibiofemoral compartment and the patellofemoral compartment were assessed by means of region of interest analysis. Pre- and post-marathon values were compared.RESULTS: There was a small increase in the T2(*) after running the marathon (30.47±5.16ms versus 29.84±4.97ms, P<0.05) while the T2(*) values before the marathon and those after the period of convalescence were similar (29.84±4.97ms versus 29.81±5.17ms, P=0.855). Regional analyses revealed lower T2(*) values in the medial tibial plateau (P<0.001).CONCLUSIONS: It appears that repetitive joint loading has a transient influence on the T2(*) values. However, this effect is small and probably not clinically relevant. The low T2(*) values in the medial tibial plateau may be related to functional demand or early cartilage degeneration.",

author = "Tobias Hesper and Miese, {Falk R} and Hosalkar, {Harish S} and Michael Behringer and Christoph Zilkens and Gerald Antoch and R{\"u}diger Krauspe and Bernd Bittersohl",

year = "2015",

month = feb,

day = "1",

doi = "10.1016/j.ejrad.2014.11.021",

language = "English",

volume = "84",

pages = "284--9",

journal = "European journal of radiology",

issn = "0720-048X",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Quantitative T2* assessment of knee joint cartilage after running a marathon

AU - Hesper, Tobias

AU - Miese, Falk R

AU - Hosalkar, Harish S

AU - Behringer, Michael

AU - Zilkens, Christoph

AU - Antoch, Gerald

AU - Krauspe, Rüdiger

AU - Bittersohl, Bernd

PY - 2015/2/1

Y1 - 2015/2/1

N2 - OBJECTIVE: To study the effect of repetitive joint loading on the T2(*) assessment of knee joint cartilage.MATERIALS AND METHODS: T2(*) mapping was performed in 10 non-professional marathon runners (mean age: 28.7±3.97 years) with no morphologically evident cartilage damage within 48h prior to and following the marathon and after a period of approximately four weeks. Bulk and zonal T2(*) values at the medial and lateral tibiofemoral compartment and the patellofemoral compartment were assessed by means of region of interest analysis. Pre- and post-marathon values were compared.RESULTS: There was a small increase in the T2(*) after running the marathon (30.47±5.16ms versus 29.84±4.97ms, P<0.05) while the T2(*) values before the marathon and those after the period of convalescence were similar (29.84±4.97ms versus 29.81±5.17ms, P=0.855). Regional analyses revealed lower T2(*) values in the medial tibial plateau (P<0.001).CONCLUSIONS: It appears that repetitive joint loading has a transient influence on the T2(*) values. However, this effect is small and probably not clinically relevant. The low T2(*) values in the medial tibial plateau may be related to functional demand or early cartilage degeneration.

AB - OBJECTIVE: To study the effect of repetitive joint loading on the T2(*) assessment of knee joint cartilage.MATERIALS AND METHODS: T2(*) mapping was performed in 10 non-professional marathon runners (mean age: 28.7±3.97 years) with no morphologically evident cartilage damage within 48h prior to and following the marathon and after a period of approximately four weeks. Bulk and zonal T2(*) values at the medial and lateral tibiofemoral compartment and the patellofemoral compartment were assessed by means of region of interest analysis. Pre- and post-marathon values were compared.RESULTS: There was a small increase in the T2(*) after running the marathon (30.47±5.16ms versus 29.84±4.97ms, P<0.05) while the T2(*) values before the marathon and those after the period of convalescence were similar (29.84±4.97ms versus 29.81±5.17ms, P=0.855). Regional analyses revealed lower T2(*) values in the medial tibial plateau (P<0.001).CONCLUSIONS: It appears that repetitive joint loading has a transient influence on the T2(*) values. However, this effect is small and probably not clinically relevant. The low T2(*) values in the medial tibial plateau may be related to functional demand or early cartilage degeneration.

U2 - 10.1016/j.ejrad.2014.11.021

DO - 10.1016/j.ejrad.2014.11.021

M3 - Journal articles

C2 - 25523822

SN - 0720-048X

VL - 84

SP - 284

EP - 289

JO - European journal of radiology

JF - European journal of radiology

IS - 2

ER -

Quantitative T2* assessment of knee joint cartilage after running a marathon

Abstract

Zugriff auf Dokument

Fingerprint

Zitation