The dynamic control ratio masks bilateral asymmetries –: A gender-specific analysis of 264 healthy and ACL-injured athletes

Isokinetic strength tests are frequently applied to assess anterior cruciate ligament (ACL) rehabilitation processes. However, diverging methodologies cause misleading conclusions. This cross-sectional study evaluated the effects of gender (male vs. female), group (healthy vs. ACL-injured) and limb (dominant/healthy vs. non-dominant/ACL-injured) on thigh muscle balance of 138 female and 126 male athletes (50% ACL-injured, averagely 12.8 months after surgery). Balance was analysed between legs (bilateral asymmetry) and between concentric knee extensor (Qcon) and eccentric knee flexor strength (Hecc) (DCR = dynamic control ratio, DCRe = DCR at the equilibrium point). Females were generally 17–27% weaker than males. Independent of gender and time after surgery, ACL-injured athletes demonstrated bilateral asymmetries (7–20%) in peak (PMQcon, PMHecc) and DCRe moments (p ≤0.030; 0.018≤ηp2≤0.215). ACL-injured athletes’ affected (24–28%) and unaffected (12–24%) hamstrings and quadriceps peak moments were significantly weaker compared to healthy athletes (p<0.001; 0.061≤ηp2≤0.362). The bilateral asymmetries of PMQcon significantly decreased from early to late self-reported rehabilitation phases (p<0.001; ηp2=0.158). Peak and DCRe moments detected bilateral asymmetries, whereas DCR revealed ~50% false negative attributions. This knowledge provides guidance for future design and interpretation of isokinetic tests.