Publikationen pro Jahr
Publikationen pro Jahr
Tim Stuckenschneider, Christopher D Askew, Annelise L Menêses, Ricarda Baake, Jan Weber, Stefan Schneider
Publikation: Beitrag in Fachzeitschrift › Übersichtsarbeiten › Forschung
BACKGROUND: Supervised exercise training alleviates motor symptoms in people with Parkinson's disease (PD). However, the efficacy of exercise to improve nonmotor symptoms such as cognitive function is less well known.
OBJECTIVE: To systematically review evidence on the efficacy of different exercise modes (coordination exercise, resistance exercise, aerobic exercise) on domain-specific cognitive function in patients with PD.
METHODS: Parallel-group randomized controlled trials published before March 2018 were included. Primary outcome measures included global cognitive function and its subdomains, and the Unified Parkinson's Disease Rating Scale was included as a secondary outcome. Methodological quality was assessed using the Physiotherapy Evidence Database scale.
RESULTS: The literature search yielded 2,000 articles, of which 11 met inclusion criteria. 508 patients (mean age 68±4 years) were included with a disease severity from 1 to 4 on the Hoehn & Yahr stage scale. Overall study quality was modest (mean 6±2, range 3-8/10). In 5 trials a significant between-group effect size (ES) was identified for tests of specific cognitive domains, including a positive effect of aerobic exercise on memory (ES = 2.42) and executive function (ES = 1.54), and of combined resistance and coordination exercise on global cognitive function (ES = 1.54). Two trials found a significant ES for coordination exercise (ES = 0.84-1.88), which led to improved executive function compared with that of non-exercising control subjects.
CONCLUSION: All modes of exercise are associated with improved cognitive function in individuals with PD. Aerobic exercise tended to best improve memory; however, a clear effect of exercise mode was not identified.
|Zeitschrift||Journal of Parkinson's disease|
|Seiten (von - bis)||73-95|
|Publikationsstatus||Veröffentlicht - 2019|
Publikation: Buch/Bericht › Dissertationsschrift
Lawlor, B., Olde Rikkert, M., Montag, C., Reuter, M., Weber, B., Polidori, M. C., Schulz, R., Abeln, V., Vogt, T., Meeusen, R. & Schneider, S.
01.05.15 → 30.04.18
Projekt: Finanziert durch Drittmittel
1 Objekt von Medienberichte