Christian Görgens

Search results

• 2024

  Urinary metabolites indicative of the administration of hypoxen monitored by liquid chromatography–high resolution/accurate mass tandem mass spectrometry

  Görgens, C., Möller, T., Guddat, S., Svambayev, E., Geyer, H., Thomas, A. & Thevis, M., 2024, In: Drug testing and analysis. 1 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Metabolite 100%
  • Tandem Mass Spectrometry 100%
  • Doping 100%
  • Liquid 100%
  • Marker 50%
• 2023

  Comparison of in vitro approaches for predicting the metabolism of the selective androgen receptor modulator RAD140

  Wagener, F., Naumann, N., Göldner, V., Görgens, C., Guddat, S., Karst, U. & Thevis, M., 08.07.2023, In: Analytical and bioanalytical chemistry. 415, p. 5657-5669 13 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • In Vitro 100%
  • Selective Androgen Receptor Modulator 100%
  • Metabolic Pathway 100%
  • Metabolite 100%
  • In Vivo 66%

• Detection of capromorelin in urine following oral and dermal routes of administration

  Sobolevsky, T., Walpurgis, K., Goergens, C., Fedoruk, M., Lewis, L., Ahrens, B. & Thevis, M., 08.09.2023, In: Drug testing and analysis. 15, 11-12, p. 1449-1453 5 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Cat 100%
  • Dog 100%
  • Pet Animal 20%
  • Appetite Stimulant 10%

• Determination of urinary deanol-N-oxide excretion profiles after ingestion of nutritional supplements containing deanol

  Krug, O., Guddat, S., Görgens, C., Piper, T., Möller, T. & Thevis, M., 2023, In: Drug testing and analysis. 15, 11-12, p. 1312-1318 7 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Urine Sampling 100%
  • Excretion 100%
  • Ingestion 100%
  • Nutrition Supplement 100%
  • Oxide 100%

• Dried blood spots for doping controls-Development of a comprehensive initial testing procedure with fully automated sample preparation

  Garzinsky, A-M., Thomas, A., Guddat, S., Görgens, C., Dib, J. & Thevis, M., 08.2023, In: Biomedical chromatography : BMC. 37, 8, e5633.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Doping 100%
  • Stimulant 20%
  • Pseudoephedrine 20%
  • Propranolol 20%
  • Cope Reaction 16%
• 2022

  Dried blood spots as option to monitor the anti-sars-cov-2 antibody response after infection or vaccination

  Carthaus, A., Görgens, C., Knoop, A-J., Geyer, H. & Thevis, M., 01.02.2022, In: German Journal of Sports Medicine. 73, 2, p. 53-60 8 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  Open Access

  • Dried Blood Spot 100%
  • Infection 57%
  • Severe Acute Respiratory Syndrome Coronavirus 2 57%
  • Antibody Response 57%
  • Antibody 28%

• Human In Vivo Metabolism and Elimination Behavior of Micro-Dosed Selective Androgen Receptor Modulator RAD140 for Doping Control Purposes

  Wagener, F., Euler, L., Görgens, C., Guddat, S. & Thevis, M., 20.07.2022, In: Metabolites. 12, 7, p. 666 1 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  Open Access

  • Doping 100%
  • Elimination 60%
  • Metabolic Pathway 40%
  • Time 40%
  • Sample 40%

• Mass spectrometry in sports drug testing-Analytical approaches and the athletes' exposome

  Thevis, M., Görgens, C., Guddat, S., Thomas, A. & Geyer, H., 2022, (Electronically/ online published ahead of print) In: Scandinavian journal of medicine & science in sports.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Drug Screening 100%
  • Mass Spectrometry 100%
  • Exposome 100%
  • Doping 100%
  • Electric Potential 28%
• 2021

  Chiral analysis of selected enantiomeric drugs relevant in doping controls

  Rubio, A., Görgens, C., Guddat, S., Piper, T., Garzinsky, A. M., Krug, O. & Thevis, M., 2021, In: Journal of Chromatography Open. 1

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Enantiomer 100%
  • Analytical Method 100%
  • Doping 100%
  • Formoterol 50%
  • Agonist 50%

• Chromatographic-mass spectrometric analysis of the urinary metabolite profile of chlorphenesin observed after dermal application of chlorphenesin-containing sunscreen

  Rubio, A., Görgens, C., Krug, O., Okano, M., Fedoruk, M., Ahrens, B., Geyer, H. & Thevis, M., 15.11.2021, In: Rapid communications in mass spectrometry : RCM. 35, 21, 9 p., e9183.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  Open Access

  • Chlorphenesin 100%
  • 4 Chlorophenoxyacetic Acid 58%
  • Sunscreen 41%
  • Meclofenoxate 33%
  • Chlorphenesin Carbamate 16%

• Comprehensive insights into the formation of metabolites of the ghrelin mimetics capromorelin, macimorelin and tabimorelin as potential markers for doping control purposes

  Lange, T., Thomas, A., Görgens, C., Bidlingmaier, M., Schilbach, K., Fichant, E., Delahaut, P. & Thevis, M., 06.2021, In: Biomedical chromatography : BMC. 35, 6, p. 1-18 18 p., e5075.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  Open Access

  • Metabolite 100%
  • Macimorelin 83%
  • Tabimorelin 66%
  • Doping 50%
  • Capromorelin 50%

• Investigations into the elimination profiles and metabolite ratios of micro-dosed selective androgen receptor modulator LGD-4033 for doping control purposes

  Wagener, F., Guddat, S., Görgens, C., Angelis, Y. S., Petrou, M., Lagojda, A., Kühne, D. & Thevis, M., 04.11.2021, (Electronically/ online published ahead of print) In: Analytical and bioanalytical chemistry. 12 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  Open Access

  • Doping 100%
  • Selective Androgen Receptor Modulator 66%
  • Urine Sampling 50%
  • Excretion 33%
  • Time 33%

• Mass spectrometric characterization of urinary hydrafinil metabolites for routine doping control purposes

  Knoop, A., Fußhöller, G., Haenelt, N., Goergens, C., Guddat, S., Geyer, H. & Thevis, M., 12.2021, In: Drug testing and analysis. 13, 11-12, p. 1915-1920 6 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  Open Access

  • Metabolite 100%
  • Doping 100%
  • Sample 40%
  • Drug Screening 40%
  • Spectroscopy 40%
• 2020

  Elevated urinary cobalt concentrations identified in routine doping controls can originate from vitamin B12

  Knoop, A., Görgens, C., Geyer, H. & Thevis, M., 15.04.2020, In: Rapid communications in mass spectrometry : RCM. 34, 7, p. e8649 3 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

• Implementation of the HIF activator IOX-2 in routine doping controls - Pilot study data

  Goergens, C., Guddat, S., Bosse, C., Knoop, A., Geyer, H. & Thevis, M., 01.09.2020, In: Drug testing and analysis. 12, 11-12, p. 1614-1619 6 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Doping 100%
  • Hypoxia Inducible Factor 60%
  • Hypoxia-Inducible Factors 60%
  • Glucuronic Acid 20%
  • Drug Screening 20%
• 2017

  The atypical excretion profile of meldonium: Comparison of urinary detection windows after single- and multiple-dose application in healthy volunteers

  Görgens, C., Guddat, S., Bosse, C., Geyer, H., Pop, V., Schänzer, W. & Thevis, M., 10.05.2017, In: Journal of pharmaceutical and biomedical analysis. 138, p. 175-179 5 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Meldonium 100%
  • Doping 80%
  • Single Drug Dose 60%
  • Multiple Drug Dose 60%
  • Urinary System 60%
• 2016

  Analyses of Meldonium (Mildronate) from Blood, Dried Blood Spots (DBS), and Urine Suggest Drug Incorporation into Erythrocytes

  Tretzel, L., Görgens, C., Geyer, H., Thomas, A., Dib, J., Guddat, S., Pop, V., Schänzer, W. & Thevis, M., 2016, In: International journal of sports medicine. 37, p. 500-502 3 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

• Mitragynine (Kratom) - monitoring in sports drug testing

  Guddat, S., Görgens, C., Steinhart, V., Schänzer, W. & Thevis, M., 2016, In: Drug testing and analysis. 8, 11-12, p. 1114–1118 5 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Doping 100%
  • Drug Screening 50%
  • Mitragynine 50%
  • Monitoring 50%
  • Health Hazard 25%

• Simplifying and expanding analytical capabilities for various classes of doping agents by means of direct urine injection high performance liquid chromatography high resolution/high accuracy mass spectrometry

  Görgens, C., Guddat, S., Thomas, A., Wachsmuth, P., Orlovius, A-K., Sigmund, G., Thevis, M. & Schänzer, W., 30.11.2016, In: Journal of pharmaceutical and biomedical analysis. 131, Nov., p. 482-496 15 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Doping 100%
  • Sample Preparation 100%
  • Drug Screening 75%
  • Mass Spectrometry 50%
  • Peptide 50%
• 2015

  "Dilute-and-inject" multi-target screening assay for highly polar doping agents using hydrophilic interaction liquid chromatography high resolution/high accuracy mass spectrometry for sports drug testing

  Görgens, C., Guddat, S., Orlovius, A-K., Sigmund, G., Thomas, A., Thevis, M. & Schänzer, W., 30.04.2015, In: Analytical and bioanalytical chemistry. 407, 18, p. 5365-5379 15 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Hydrophilic Interaction Chromatography 100%
  • Accuracy 33%
  • Glycerol 33%
  • Analeptic Agent 33%
  • Concentration 33%

• Mildronate (Meldonium) in professional sports - monitoring doping control urine samples using hydrophilic interaction liquid chromatography - high resolution/high accuracy mass spectrometry

  Görgens, C., Guddat, S., Dib, J., Geyer, H., Schänzer, W. & Thevis, M., 05.04.2015, In: Drug testing and analysis.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Meldonium 100%
  • Doping 50%
  • Mass Spectrometry 25%
  • Decision-Making Process 25%
  • Drugs in Sports 25%

• Simplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry

  Thomas, A., Görgens, C., Guddat, S., Thieme, D., Delanna, F., Schänzer, W. & Thevis, M., 18.11.2015, In: Journal of Separation Science.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Peptide 100%
  • Sample 50%
  • Procedure 50%
  • Doping 50%
  • Drug Screening 50%
• 2014

  Screening and confirmation of myo-inositol trispyrophosphate (ITPP) in human urine by hydrophilic interaction liquid chromatography high resolution / high accuracy mass spectrometry for doping control purposes

  Görgens, C., Guddat, S., Schänzer, W. & Thevis, M., 2014, In: Drug testing and analysis. 6, 11-12, p. 1102-7 6 p.

  Publication: Contribution to journal › Journal articles › Research › peer-review

  • Inositol 100%
  • Screening 75%
  • Hydrophilic Interaction Chromatography 50%
  • Multiple Sclerosis 50%
  • Doping 37%