Current role of LC–MS(/MS) in doping control

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Abstract

Liquid chromatography–(tandem) mass spectrometry (LC–MS/MS) has revolutionized the detection assays used in doping control analysis over the last decade. New methods have enabled the determination of drugs that were formerly difficult to detect or undetectable at preceding sample concentrations, and complex and/or time-consuming procedures based on alternative chromatographic–mass spectrometric or immunochemical principles have been replaced by faster, more comprehensive and robust assays. A critical overview of the contributions of LC–MS(/MS) to sports drug testing is provided, including recent developments regarding low and high molecular weight drugs. Verf.-Referat
Translated title of the contributionAktuelle Bedeutung von LC–MS(/MS) in der Dopingkontrolle
Original languageEnglish
JournalAnalytical and bioanalytical chemistry
Volume388
Pages (from-to)1351-1358
Number of pages8
ISSN1618-2642
Publication statusPublished - 2007

Citation