Effects of endurance exercise on the urinary proteome analyzed by 2D-PAGE and Orbitrap mass spectrometry

Publication: Chapter in Book/Report/Conference proceedingConference contribution - Article for conferenceResearch


Exercise-induced proteinuria is a well-known phenomenon and influencing parameters such as intensity and duration were studied extensively. While usually total protein or albumin was measured for determination of proteinuria, the investigation of qualitative changes of the urinary proteome may give insight into biochemical processes connected to strenuous physical exercise. The aim of the present study was to search for qualitative and quantitative differences in the urinary proteome of athletes before and after endurance exercise by means of 2D-PAGE and to identify the altered proteins by nano-UPLC Orbitrap mass spectrometry. It shall serve as a starting point to build up individual 2 D-PAGE protein maps of athletes. Verf.-Referat
Original languageGerman
Title of host publicationRecent advances in doping analysis (18) : Proceedings of the Manfred-Donike-Workshop, 28th Cologne Workshop on Dope Analysis : 7th to 12th March 2010
EditorsWilhelm Schänzer, Hans Geyer, A. Gotzmann, Ute Mareck
Number of pages4
PublisherSportverlag Strauß
Publication date2010
Publication statusPublished - 2010
EventCologne Workshop on Dope Analysis - Köln, Germany
Duration: 07.03.201012.03.2010
Conference number: 28