Efficacy of prehabilitation prior to cardiac surgery: a systematic review and meta-analysis

Carolin Steinmetz, Birna Bjarnason-Wehrens, Thomas Walther, Tim Fabian Schaffland, Claudia Walther

Publication: Contribution to journalJournal articlesResearchpeer-review

Abstract

OBJECTIVE: Patients awaiting cardiac surgery seem to benefit from exercise-based prehabilitation, but the impact on different perioperative outcomes compared with standard care is still unclear.

DESIGN: Eligible nonrandomized/randomized controlled studies investigating the impact of exercise-based prehabilitation in adults scheduled for elective cardiac surgery were searched on December 16, 2020, from electronic databases, including MEDLINE, CENTRAL, and CINAHL. The data were pooled and a meta-analysis was conducted.

RESULTS: Of 1490 abstracts, six studies ( n = 665) were included into the review and meta-analysis. At postintervention interval and at postsurgery interval, 6-min-walking distance improved significantly in exercise-based prehabilitation group compared with controls (mean difference, 75.4 m; 95% confidence interval, 13.7 to 137.1 m, P = 0.02, and 30.5 m, 95% confidence interval, 8.5 to 52.6 m, P = 0.007, respectively). Length of hospital stay was significantly shorter in exercise-based prehabilitation group (mean difference, -1.00 day; 95% confidence interval, -1.78 to -0.23 day, P = 0.01). Participation in exercise-based prehabilitation revealed a significant decrease in the risk of postoperative atrial fibrillation in patients 65 yrs or younger (risk ratio, 0.34; 95% confidence interval, 0.14 to 0.83, P = 0.02).

CONCLUSIONS: The participation in exercise-based prehabilitation significantly improves postintervention and postsurgery 6-min walking distance, length of hospital stay, and decreases the risk of postoperative atrial fibrillation in patients 65 yrs or younger compared with controls.

Original languageEnglish
JournalAmerican journal of physical medicine & rehabilitation / Association of Academic Physiatrists
VolumePublish Ahead of Print
Issue number4
Pages (from-to)323-330
Number of pages8
DOIs
Publication statusPublished - 01.04.2023

Research areas and keywords

  • Adult
  • Atrial Fibrillation
  • Cardiac Surgical Procedures
  • Exercise
  • Humans
  • Postoperative Complications/prevention & control
  • Preoperative Care
  • Preoperative Exercise

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