Gas Exchange Kinetics Following Concentric-Eccentric Isokinetic Arm and Leg Exercise

Uwe Drescher, Swapan Mookerjee, Ansgar Steegmanns, Axel Knicker, Uwe Hoffmann

Publication: Contribution to journalJournal articlesResearchpeer-review


To evaluate the effects of exercise velocity (60, 150, 240 deg·s-1) and muscle mass (arm vs leg) on changes in gas exchange and arterio-venous oxygen content difference (avDO2) following high-intensity concentric-eccentric isokinetic exercise.
Fourteen subjects (26.9±3.1 years) performed a 3x20-repetition isokinetic exercise protocol. Recovery beat-to-beat cardiac output (CO) and breath-by-breath gas exchange were recorded to determine post-exercise half-time (t1/2) for oxygen uptake (V’O2pulm), carbon dioxide output (V’CO2pulm), and ventilation (V’E).
Significant differences of the t1/2 values were identified between 60 and 150 deg·s-1. Significant differences in the t1/2 values were observed between V’O2pulm and V’CO2pulm and between V’CO2pulm and V’E. The time to attain the first avDO2-peak showed significant differences between arm and leg exercise.
The present study illustrates, that V’O2pulm kinetics are distorted due to non-linear CO dynamics. Therefore, it has to be taken into account, that V’O2pulm may not be a valuable surrogate for muscular oxygen uptake kinetics in the recovery phases.
Original languageEnglish
JournalRespiratory Physiology & Neurobiology
Pages (from-to)53-60
Number of pages8
Publication statusPublished - 2017


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