THE SINGLE PILL CONCEPT LEADS TO IMPROVED PERSISTENCE OF MEDICATION, CLINICAL OUTCOMES AND REDUCED ALL‐CAUSE MORTALITY IN HYPERTENSIVE PATIENTS – RESULTS FROM THE START PROJECT

Hans-Georg Predel; Burkhard Weisser; Sven Wassmann; Anton Gillessen; Jörg Blettenberg; Valérie Fournier; Andrea Noetel; Olaf Randerath; Michael Böhm; Roland E. Schmieder

doi:10.1097/01.hjh.0000748928.45804.cf

THE SINGLE PILL CONCEPT LEADS TO IMPROVED PERSISTENCE OF MEDICATION, CLINICAL OUTCOMES AND REDUCED ALL‐CAUSE MORTALITY IN HYPERTENSIVE PATIENTS – RESULTS FROM THE START PROJECT

Hans-Georg Predel, Burkhard Weisser, Sven Wassmann, Anton Gillessen, Jörg Blettenberg, Valérie Fournier, Andrea Noetel, Olaf Randerath, Michael Böhm, Roland E. Schmieder

Preventive and Rehabilitative Sports and Performance Medicine

Publication: Contribution to journal › Journal articles › Research › peer-review

Abstract

Objective:
ESC/ESH guidelines for the treatment of arterial hypertension recommend to start treatment with a single pill combination (SP) of a renin–angiotensin–system (RAS) blocker with a diuretic or a calcium channel blocker to improve drug persistence, blood pressure (BP) control and to reduce cardiovascular events. Escalation should be a SP triple combination. We aimed to assess whether the SP concept is superior to identical free combinations (FC) in terms of clinical outcomes, including all-cause mortality.

Original language	English
Journal	Journal of Hypertension
Volume	39
Issue number	e-Supplement 1
Pages (from-to)	e378
Number of pages	1
ISSN	0263-6352
DOIs	https://doi.org/10.1097/01.hjh.0000748928.45804.cf
Publication status	Published - 04.2021

Access to Document

10.1097/01.hjh.0000748928.45804.cf

Citation

Predel, H-G., Weisser, B., Wassmann, S., Gillessen, A., Blettenberg, J., Fournier, V., Noetel, A., Randerath, O., Böhm, M., & Schmieder, R. E. (2021). THE SINGLE PILL CONCEPT LEADS TO IMPROVED PERSISTENCE OF MEDICATION, CLINICAL OUTCOMES AND REDUCED ALL‐CAUSE MORTALITY IN HYPERTENSIVE PATIENTS – RESULTS FROM THE START PROJECT. Journal of Hypertension, 39( e-Supplement 1), e378. https://doi.org/10.1097/01.hjh.0000748928.45804.cf

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title = "THE SINGLE PILL CONCEPT LEADS TO IMPROVED PERSISTENCE OF MEDICATION, CLINICAL OUTCOMES AND REDUCED ALL‐CAUSE MORTALITY IN HYPERTENSIVE PATIENTS – RESULTS FROM THE START PROJECT",

abstract = "Objective: ESC/ESH guidelines for the treatment of arterial hypertension recommend to start treatment with a single pill combination (SP) of a renin–angiotensin–system (RAS) blocker with a diuretic or a calcium channel blocker to improve drug persistence, blood pressure (BP) control and to reduce cardiovascular events. Escalation should be a SP triple combination. We aimed to assess whether the SP concept is superior to identical free combinations (FC) in terms of clinical outcomes, including all-cause mortality.",

author = "Hans-Georg Predel and Burkhard Weisser and Sven Wassmann and Anton Gillessen and J{\"o}rg Blettenberg and Val{\'e}rie Fournier and Andrea Noetel and Olaf Randerath and Michael B{\"o}hm and Schmieder, {Roland E.}",

year = "2021",

month = apr,

doi = "10.1097/01.hjh.0000748928.45804.cf",

language = "English",

volume = "39",

pages = "e378",

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issn = "0263-6352",

publisher = "Lippincott Williams and Wilkins Ltd.",

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Predel, H-G, Weisser, B, Wassmann, S, Gillessen, A, Blettenberg, J, Fournier, V, Noetel, A, Randerath, O, Böhm, M & Schmieder, RE 2021, 'THE SINGLE PILL CONCEPT LEADS TO IMPROVED PERSISTENCE OF MEDICATION, CLINICAL OUTCOMES AND REDUCED ALL‐CAUSE MORTALITY IN HYPERTENSIVE PATIENTS – RESULTS FROM THE START PROJECT', Journal of Hypertension, vol. 39, no. e-Supplement 1, pp. e378. https://doi.org/10.1097/01.hjh.0000748928.45804.cf

THE SINGLE PILL CONCEPT LEADS TO IMPROVED PERSISTENCE OF MEDICATION, CLINICAL OUTCOMES AND REDUCED ALL‐CAUSE MORTALITY IN HYPERTENSIVE PATIENTS – RESULTS FROM THE START PROJECT. / Predel, Hans-Georg; Weisser, Burkhard; Wassmann, Sven et al.
In: Journal of Hypertension, Vol. 39, No. e-Supplement 1, 04.2021, p. e378.

Publication: Contribution to journal › Journal articles › Research › peer-review

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AU - Predel, Hans-Georg

AU - Weisser, Burkhard

AU - Wassmann, Sven

AU - Gillessen, Anton

AU - Blettenberg, Jörg

AU - Fournier, Valérie

AU - Noetel, Andrea

AU - Randerath, Olaf

AU - Böhm, Michael

AU - Schmieder, Roland E.

PY - 2021/4

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