Alternative steroid profiling : reference ranges for urinary endogenous steroids in a Caucasian population of athletes

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A comprehensive screening method for steroid profiling was developed covering 29 steroid metabolites. Additionally, 10 steroid ratios were evaluated. Based upon a reference population of more than 3000 samples from healthy athletes the reference values were established at 3 different levels: 97.5%, 99% and 99.9%. Using the extended method and the reference ranges, 2 additional metabolites from 6-oxo-Adion were identified; 6ß-OH-Andro and 6ß-OH-Etio could stretch the detection time for 6-oxo-Adion administration until 36h. In the case of 7-keto-DHEA, 7α-OH-T can be regarded as additional specific metabolite. 7-keto-DHEA can be detected 36h after intake although steroid ratios indicate prolonged changes up to 48h of the steroid profile. Aus dem Text
OriginalspracheDeutsch
TitelRecent advances in doping analysis (17) : Proceedings of the Manfred Donike Workshop ; 27th Cologne Workshop on Dope Analysis, 1st to 6th March 2009
Redakteure/-innenWilhelm Schänzer, Hans Geyer, A. Gotzmann, Ute Mareck
Seitenumfang10
Herausgeber/inSportverlag Strauß
Erscheinungsdatum2009
Seiten81-90
PublikationsstatusVeröffentlicht - 2009
VeranstaltungCologne Workshop on Dope Analysis - Köln, Deutschland
Dauer: 01.03.200906.03.2009
Konferenznummer: 27

ID: 189451

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