Analytical challenges in the detection of peptide hormones for anti-doping purposes

Publikationen: Beitrag in FachzeitschriftZeitschriftenaufsätzeForschung

AutorInnen

  • Osquel Barroso
  • David J Handelsman
  • Christian Strasburger
  • Mario Thevis

Forschungseinrichtungen

Details

Although significant progress has been achieved during the past few years with the introduction of new assays and analytical methodologies, the detection and quantification of protein analytes, in particular of peptide hormones, continues to pose analytical challenges for the World Anti-Doping Agency-accredited anti-doping laboratories. In this article, the latest achievements in the application of MS-based methodologies and specific biochemical and immunological assays to detect some of the prohibited substances listed in section S2 of the World Anti-Doping Agency List of Prohibited Substances and Methods are reviewed. In addition, we look towards the future by focusing on some of the most promising analytical approaches under development for the detection of so-called 'biomarkers of doping'.

OriginalspracheEnglisch
ZeitschriftBioanalysis
Jahrgang4
Heft13
Seiten (von - bis)1577-1590
Seitenumfang14
DOIs
PublikationsstatusVeröffentlicht - 01.07.2012

ID: 129732

DOI

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