Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report

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Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia : A Case Report. / Bühl, Linda; Abel, Thomas; Wolf, Florian; Oberste, Max; Bloch, Wilhelm; Hallek, Michael; Elter, Thomas; Zimmer, Philipp.

in: Integrative cancer therapies, Jahrgang 18, 01.02.2019.

Publikationen: Beitrag in FachzeitschriftZeitschriftenaufsätzeForschungBegutachtung

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@article{4fbf82764c64446ab8422d3bc2d7aecc,
title = "Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report",
abstract = "In patients with hematological malignancies, exercise is studied as a supportive measure with potential benefits on therapy and disease-related side effects. However, clinical trials have not yet integrated people with Down syndrome (DS), although this disability is associated with an increased risk for hematological malignancies. Therefore, we examined safety and feasibility of a mixed-modality exercise intervention in a male with DS undergoing high-dose chemotherapy for acute lymphoblastic leukemia. Furthermore, physical capacity and fatigue were assessed. Exercise sessions took place 3 times/wk over a 5-week period. Adherence to the exercise program was 100%, and no serious adverse events occurred. In contrast to the training sessions, applied endurance testing was not feasible. Furthermore, maintenance of fatigue level was observed. In conclusion, cancer patients with DS suffering from leukemia should not be excluded from physical activity or exercise programs.",
keywords = "Down syndrome, cancer, exercise, fatigue, leukemia, physical activity",
author = "Linda B{\"u}hl and Thomas Abel and Florian Wolf and Max Oberste and Wilhelm Bloch and Michael Hallek and Thomas Elter and Philipp Zimmer",
note = "Online: 22.02.2019",
year = "2019",
month = feb,
day = "1",
doi = "10.1177/1534735419832358",
language = "English",
volume = "18",
journal = "Integrative cancer therapies",
issn = "1534-7354",
publisher = "SAGE Publications Inc.",

}

RIS

TY - JOUR

T1 - Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia

T2 - A Case Report

AU - Bühl, Linda

AU - Abel, Thomas

AU - Wolf, Florian

AU - Oberste, Max

AU - Bloch, Wilhelm

AU - Hallek, Michael

AU - Elter, Thomas

AU - Zimmer, Philipp

N1 - Online: 22.02.2019

PY - 2019/2/1

Y1 - 2019/2/1

N2 - In patients with hematological malignancies, exercise is studied as a supportive measure with potential benefits on therapy and disease-related side effects. However, clinical trials have not yet integrated people with Down syndrome (DS), although this disability is associated with an increased risk for hematological malignancies. Therefore, we examined safety and feasibility of a mixed-modality exercise intervention in a male with DS undergoing high-dose chemotherapy for acute lymphoblastic leukemia. Furthermore, physical capacity and fatigue were assessed. Exercise sessions took place 3 times/wk over a 5-week period. Adherence to the exercise program was 100%, and no serious adverse events occurred. In contrast to the training sessions, applied endurance testing was not feasible. Furthermore, maintenance of fatigue level was observed. In conclusion, cancer patients with DS suffering from leukemia should not be excluded from physical activity or exercise programs.

AB - In patients with hematological malignancies, exercise is studied as a supportive measure with potential benefits on therapy and disease-related side effects. However, clinical trials have not yet integrated people with Down syndrome (DS), although this disability is associated with an increased risk for hematological malignancies. Therefore, we examined safety and feasibility of a mixed-modality exercise intervention in a male with DS undergoing high-dose chemotherapy for acute lymphoblastic leukemia. Furthermore, physical capacity and fatigue were assessed. Exercise sessions took place 3 times/wk over a 5-week period. Adherence to the exercise program was 100%, and no serious adverse events occurred. In contrast to the training sessions, applied endurance testing was not feasible. Furthermore, maintenance of fatigue level was observed. In conclusion, cancer patients with DS suffering from leukemia should not be excluded from physical activity or exercise programs.

KW - Down syndrome

KW - cancer

KW - exercise

KW - fatigue

KW - leukemia

KW - physical activity

UR - https://www.mendeley.com/catalogue/d8a4792b-370a-3c54-a1b1-706afa9eb06e/

U2 - 10.1177/1534735419832358

DO - 10.1177/1534735419832358

M3 - Journal articles

C2 - 30795696

VL - 18

JO - Integrative cancer therapies

JF - Integrative cancer therapies

SN - 1534-7354

ER -

ID: 3653150