SERUM CARTILAGE BIOMARKERS IN RESPONSE TO 21 DAYS BED REST WITH EXERCISE AND NUTRITION COUNTERMEASURES

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SERUM CARTILAGE BIOMARKERS IN RESPONSE TO 21 DAYS BED REST WITH EXERCISE AND NUTRITION COUNTERMEASURES. / Dreiner, Maren; Zaucke, Frank; Mündermann, Annegret; Liphardt, Anna-Maria; Niehoff, Anja.

in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Jahrgang 30, Nr. Supplement 1, 01.04.2022, S. 105.

Publikationen: Beitrag in FachzeitschriftKonferenz-Abstract in FachzeitschriftForschungBegutachtung

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@article{3e40b114055c4a74ad31aae6038b11ac,
title = "SERUM CARTILAGE BIOMARKERS IN RESPONSE TO 21 DAYS BED REST WITH EXERCISE AND NUTRITION COUNTERMEASURES",
abstract = " Immobilization is one major risk factor for osteoarthritis as longer periods of unloading can initiate catabolic processes and cause cartilage degeneration. Bed rest studies are an excellent standardized model for simulating not only the effects of spaceflight but also to investigate the impact of longer periods of immobilization and possible countermeasures to prevent articular cartilage degeneration. Biomarkers of cartilage metabolism are sensitive to changes in the biological and mechanical environment and can indicate early changes in cartilage homeostasis. The purpose of the study was to investigate 1) the effect of 21 days of immobilization on a broad spectrum of serum cartilage biomarkers and 2) the efficiency of a resistive vibration exercise protocol with and without nutritional supplements as countermeasures over 21 days bed rest to avoid changes in cartilage metabolism.",
author = "Maren Dreiner and Frank Zaucke and Annegret M{\"u}ndermann and Anna-Maria Liphardt and Anja Niehoff",
year = "2022",
month = apr,
day = "1",
language = "English",
volume = "30",
pages = "105",
journal = "Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society",
issn = "1063-4584",
publisher = "W.B. Saunders Ltd",
number = "Supplement 1",

}

RIS

TY - JOUR

T1 - SERUM CARTILAGE BIOMARKERS IN RESPONSE TO 21 DAYS BED REST WITH EXERCISE AND NUTRITION COUNTERMEASURES

AU - Dreiner, Maren

AU - Zaucke, Frank

AU - Mündermann, Annegret

AU - Liphardt, Anna-Maria

AU - Niehoff, Anja

PY - 2022/4/1

Y1 - 2022/4/1

N2 - Immobilization is one major risk factor for osteoarthritis as longer periods of unloading can initiate catabolic processes and cause cartilage degeneration. Bed rest studies are an excellent standardized model for simulating not only the effects of spaceflight but also to investigate the impact of longer periods of immobilization and possible countermeasures to prevent articular cartilage degeneration. Biomarkers of cartilage metabolism are sensitive to changes in the biological and mechanical environment and can indicate early changes in cartilage homeostasis. The purpose of the study was to investigate 1) the effect of 21 days of immobilization on a broad spectrum of serum cartilage biomarkers and 2) the efficiency of a resistive vibration exercise protocol with and without nutritional supplements as countermeasures over 21 days bed rest to avoid changes in cartilage metabolism.

AB - Immobilization is one major risk factor for osteoarthritis as longer periods of unloading can initiate catabolic processes and cause cartilage degeneration. Bed rest studies are an excellent standardized model for simulating not only the effects of spaceflight but also to investigate the impact of longer periods of immobilization and possible countermeasures to prevent articular cartilage degeneration. Biomarkers of cartilage metabolism are sensitive to changes in the biological and mechanical environment and can indicate early changes in cartilage homeostasis. The purpose of the study was to investigate 1) the effect of 21 days of immobilization on a broad spectrum of serum cartilage biomarkers and 2) the efficiency of a resistive vibration exercise protocol with and without nutritional supplements as countermeasures over 21 days bed rest to avoid changes in cartilage metabolism.

UR - https://doi.org/10.1016/j.joca.2022.02.133

M3 - Conference abstract in journal

VL - 30

SP - 105

JO - Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society

JF - Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society

SN - 1063-4584

IS - Supplement 1

ER -

ID: 6600379