Adipokine-Myokine-Hepatokine Compartment-System in mothers and children: an explorative study

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Authors

  • Clara Deibert
  • Nina Ferrari
  • A. Flöck
  • W.M. Merz
  • U. Gembruch
  • Walter Lehmacher
  • Christina Ehrhardt
  • Christine Graf

Research units

Details

Maternal lifestyle during pregnancy has an effect of gestational development and neonatal outcome. Overweight gravidas and gravidas with excessive weight gain have an increased risk of gestational complications and neonatal metabolic disorder. The underlying mechanisms are still under discussion, but the hormonally active fat mass and its biomarkers, adipocytokines, may play a key role by potentially having a direct impact on the metabolic homeostasis of the system in concert with other biomarkers like hepatokines and myokines. Up to now little is known in terms of lifestyle habits and their effect on this complex model on maternal and fetal outcome. Therefore, we aim to investigate the influence of maternal lifestyle clusters during pregnancy on the maternal and fetal biomarkers of compartments, specifically those implying maternal fat and muscle mass, maternal liver and the placenta and who are associated with maternal body composition and birth weight.
Original languageEnglish
JournalContemporary Clinical Trials Communications
Volume3
Pages (from-to)1-5
Number of pages5
DOIs
Publication statusPublished - 12.02.2016

ID: 1722961

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