Analysis of heart rate and oxygen uptake kinetics studied by two different pseudo-random binary sequence work rate amplitudes

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Purpose The aim of the study was to compare the kinetics responses of heart rate (HR), pulmonary (V’O2pulm) and predicted muscular (V’O2musc) oxygen uptake between two different pseudo-random binary sequence (PRBS) work rate (WR) amplitudes both below anaerobic threshold. Methods Eight healthy individuals performed two PRBS WR protocols implying changes between 30W to 80W and between 30W to 110W. HR and V’O2pulm were measured beat-to-beat and breath-by-breath, respectively. V’O2musc was estimated applying the approach of Hoffmann et al. (Eur J Appl Physiol 113: 1745-1754, 2013) considering a circulatory model for venous return and cross-correlation functions (CCF) for the kinetics analysis. Results HR and V’O2musc kinetics seem to be independent of WR intensity (p > 0.05). V’O2pulm kinetics show prominent differences in the lag of the CCF maximum (39 ± 9s; 31 ± 4s; p < 0.05). Conclusions A mean difference of 14 W between the PRBS WR amplitudes impacts venous return significantly, while HR and V’O2musc kinetics remain unchanged.
Original languageEnglish
JournalRespiratory Physiology & Neurobiology
Volume240
Pages (from-to)70-80
Number of pages11
Publication statusPublished - 04.03.2017

ID: 2983671

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