BRECA-MALE Studie: Einflüsse von zielgerichteter Bewegungstherapie auf therapiebedingte Nebenwirkungen bei Männern nach Brustkrebs. Eine Pilotstudie

Publications: Book/ReportDissertations


Research units


Introduction: There is ample evidence for exercise/physical activity promoting a positive impact on cancer therapy related side effects. (Patel et al. 2019, Cormie et al. 2018, Fuller et al. 2018, Baumann et al. 2017 b), Cheema et al. 2014).
Due to its rarity no exercise studies have been conducted in the field of male breast cancer in the aftercare, yet. This pilot study focuses on the feasibility and the impact of a moderate and vigorous web-based resistance and endurance training on cancer related side effects.
Methods:14 males (60,41±9,36 years) in the breast-cancer aftercare completed a 7-month, web-based randomized controlled exercise intervention study in the cross over design.
The intervention took place three times a week for 30 minutes (2 times a week endurance training and once a week six selected strength exercises), following an individual heart rate specification. Depending on the allocated group the intensity was either moderate- (40-50% maxHR; RPE:11), or vigorous (70-80% maxHR; RPE:15) for the first three months. After a four-week wash- out period, without any intervention, participants changed the exercise intensity for another three months. The feasibility will be determined by the dropout rate. To evaluate the cancer related side effects five questionnaires were included. The physical fitness was measured via spiroergometry, on each of the four measurement times.
Results: The dropout rate was 36% in total (t1: n= 22 to t4: n= 14). There are significant treatment effects at the expense of the intense Training for “physical function” (p= 0,037*) and in favor of the moderate intensity for “social function” (p= 0,016*).
The strongest, but not statistically significant improvement was observed for “breast symptoms” (p=0,095), after following the moderate training. Due to a carry-over effect for the VO2max no further calculations could be made to determine the treatment effect.
Conclusion: This web-based strength and endurance training of a rare cancer entity in the aftercare demonstrated its feasibility. Moderate intense training seems to benefit the most, to mitigate treatment side effects. This applies especially to weaker and more symptomatic patients at the beginning of the study. Further studies are needed to develop an optimized gender specific rehabilitation aftercare for men after breast cancer
Original languageGerman
Place of PublicationKöln
PublisherDeutsche Sporthochschule Köln
Number of pages201
Publication statusPublished - 2021

ID: 6614343


View graph of relations