TY - JOUR
T1 - Cellular immune response to acute exercise
T2 - Comparison of endurance and resistance exercise
AU - Schlagheck, Marit Lea
AU - Walzik, David
AU - Joisten, Niklas
AU - Koliamitra, Christina
AU - Hardt, Luca
AU - Metcalfe, Alan J
AU - Wahl, Patrick
AU - Bloch, Wilhelm
AU - Schenk, Alexander
AU - Zimmer, Philipp
N1 - © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - OBJECTIVES: Exercise-induced cellular mobilization might play a role in treatment and prevention of several diseases. However, little is known about the impact of different exercise modalities on immune cell mobilization and clinical cellular inflammation markers. Therefore, the present study aimed to investigate differences between acute endurance exercise (EE) and resistance exercise (RE) on cellular immune alterations.METHODS: 24 healthy men conducted an acute EE (cycling at 60% of peak power output) and RE (five exercise machines at 70% of the one-repetition maximum) session lasting 50 minutes in randomized order. Blood samples were collected before, after and one hour after exercise cessation. Outcomes included counts and proportions of leukocytes, neutrophils (NEUT), lymphocytes (LYM), LYM subsets, CD4/CD8 ratio and the clinical cellular inflammation markers NEUT/LYM ratio (NLR), platelets/LYM ratio (PLR) and systemic immune inflammation index (SII).RESULTS: Alterations in all outcomes were revealed except for CD8+ T cells, CD4/CD8 ratio, NLR and PLR. EE induced a stronger cellular immune response and provoked alterations in more immune cell populations than RE. SII was altered only after EE.CONCLUSION: An acute EE session causes a stronger mobilization of immune cells than RE. Additionally, SII represents an integrative marker to depict immunological alterations.
AB - OBJECTIVES: Exercise-induced cellular mobilization might play a role in treatment and prevention of several diseases. However, little is known about the impact of different exercise modalities on immune cell mobilization and clinical cellular inflammation markers. Therefore, the present study aimed to investigate differences between acute endurance exercise (EE) and resistance exercise (RE) on cellular immune alterations.METHODS: 24 healthy men conducted an acute EE (cycling at 60% of peak power output) and RE (five exercise machines at 70% of the one-repetition maximum) session lasting 50 minutes in randomized order. Blood samples were collected before, after and one hour after exercise cessation. Outcomes included counts and proportions of leukocytes, neutrophils (NEUT), lymphocytes (LYM), LYM subsets, CD4/CD8 ratio and the clinical cellular inflammation markers NEUT/LYM ratio (NLR), platelets/LYM ratio (PLR) and systemic immune inflammation index (SII).RESULTS: Alterations in all outcomes were revealed except for CD8+ T cells, CD4/CD8 ratio, NLR and PLR. EE induced a stronger cellular immune response and provoked alterations in more immune cell populations than RE. SII was altered only after EE.CONCLUSION: An acute EE session causes a stronger mobilization of immune cells than RE. Additionally, SII represents an integrative marker to depict immunological alterations.
KW - cellular immune system
KW - endurance exercise
KW - exercise
KW - inflammation
KW - resistance exercise
UR - https://www.mendeley.com/catalogue/8793b555-dba1-3681-8ec4-41e460fb60d3/
U2 - 10.1111/ejh.13412
DO - 10.1111/ejh.13412
M3 - Journal articles
C2 - 32221992
SN - 1600-0609
VL - 105
SP - 75
EP - 84
JO - European journal of haematology
JF - European journal of haematology
IS - 1
ER -