Do dried blood spots have the potential to support result management processes in routine sports drug testing? - Part 2: Proactive sampling for follow-up investigations concerning atypical or adverse analytical findings

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Abstract

Capillary blood sampled as dried blood spot (DBS) has shown substantial potential as test matrix in sports drug testing in various different settings, enabling the analysis of numerous different drugs and/or their respective metabolites. In addition to established beneficial aspects of DBS specimens in general (such as the minimally invasive and non-intrusive nature, and simplified sample transport), a yet unexplored advantage of DBS in the anti-doping context could be the opportunity of preserving a source of information complementary to routine doping controls performed in urine or venous blood. Whenever follow-up investigations are warranted or required, frequently collected and stored (but yet not analyzed) DBS samples could be target-tested for the compound(s) in question, in order to contribute to results management and decision-making processes.
Original languageEnglish
JournalDrug testing and analysis
Volume13
Issue number3
Pages (from-to)505-509
Number of pages5
ISSN1942-7603
DOIs
Publication statusPublished - 03.2021

Research areas and keywords

  • Capillaries
  • Doping in Sports/prevention & control
  • Dried Blood Spot Testing/methods
  • Humans
  • Specimen Handling/methods
  • Substance Abuse Detection/methods
  • doping
  • atypical finding
  • adverse analytical finding
  • dried blood spot
  • sport

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