Ischemic Preconditioning Blunts Eccentric Exercise-Induced Muscle Damage Due To Reduced Oxidative Stress?

Jan-Frieder Harmsen, Alexander Franz, Constantin Mayer, Michael Behringer, Bjoern Braunstein, Robert Rein, Christoph Zilkens

Publication: Chapter in Book/Report/Conference proceedingConference contribution - Other conference contributionsResearchpeer-review

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Abstract

The purpose of this study was to investigate if ischemic preconditioning (IPC) prior to eccentric exercise of the elbow flexors leads to alterations in muscle oxygen saturation (SmO2) during loading. Additionally, parameters of muscle damage, like serum creatine kinase, were assessed following the loading protocol. Nineteen untrained males were allocated into two groups: (1) performing IPC prior to eccentric exercise (IPC+ECC; n=10) and (2) performing eccentric exercise only (n=9). Muscle damage parameters were significantly lower in IPC+ECC (p<0.05). The drop of SmO2 during eccentric loading (ischemia) as well as the subsequent increase of SmO2 (reperfusion) were lower in IPC+ECC (p<0.05). These findings indicate that reduced oxidative stress might have contributed to the blunted muscle damage response seen after IPC.
Original languageEnglish
Title of host publicationISBS Proceedings Archive : 36th Conference of the International Society of Biomechanics in Sports
Number of pages4
PublisherInternational Society of Biomechanics in Sports
Publication date2018
Publication statusPublished - 2018
EventInternational Society of Biomechanics in Sports (ISBS) - Auckland, New Zealand
Duration: 10.09.201814.09.2018
Conference number: 36

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