Oral Contraceptives Do Not Affect Physiological Responses to Strength Exercise

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Oral Contraceptives Do Not Affect Physiological Responses to Strength Exercise. / Umlauff, Lisa; Weil, Peter; Zimmer, Philipp; Hackney, Anthony C; Bloch, Wilhelm; Schumann, Moritz.

In: Journal of strength and conditioning research / National Strength & Conditioning Association, Vol. 35, No. 4, 01.04.2021, p. 894-901.

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@article{48433d9484d243cba63f1ac96a5df21d,
title = "Oral Contraceptives Do Not Affect Physiological Responses to Strength Exercise",
abstract = "ABSTRACT: Umlauff, L, Weil, P, Zimmer, P, Hackney, AC, Bloch, W, and Schumann, M. Oral contraceptives do not affect physiological responses to strength exercise. J Strength Cond Res 35(4): 894-901, 2021-This study investigated the effect of oral contraceptive (OC) use on acute changes in steroid hormone concentrations and tryptophan (TRP) metabolites in response to strength exercise. Twenty-one women (age: 23 ± 3 years), 8 combined OC users (OC group) and 13 naturally cycling women (menstrual cycle [MC] group), participated. Testing was performed during the pill-free interval for the OC group and the follicular phase for the MC group. Subjects completed an intense strength exercise protocol (4 × 10 repetitions back squat). Blood samples were taken at baseline (T0), post-exercise (T1), and after 24 hours (T2) to determine serum concentrations of cortisol, estradiol, testosterone, TRP, and kynurenine (KYN). Statistical significance was defined as p ≤ 0.05. At T0, the OC group showed higher cortisol (OC: 493.7 ± 47.1 ng·mL-1, MC: 299.1 ± 62.7 ng·mL-1, p < 0.001) and blood lactate (OC: 1.81 ± 0.61 mmol·L-1, MC: 1.06 ± 0.30 mmol·L-1, p = 0.001) and lower estradiol (OC: 31.12 ± 4.24 pg·mL-1, MC: 38.34 ± 7.50 pg·mL-1, p = 0.023) and KYN (OC: 1.15 ± 0.23 µmol·L-1, MC: 1.75 ± 0.50 µmol·L-1, p = 0.005). No significant interactions (group × time, p > 0.05) were found for the hormones and TRP metabolites assessed. Oral contraceptive use did not affect the physiological response of steroid hormones and TRP metabolites to acute strength exercise during the low hormone phase of the contraceptive or MC in healthy young women, even when some baseline concentrations differed between groups. Consequently, these findings provide important implications for practitioners testing heterogeneous groups of female athletes.",
keywords = "Adult, Contraceptives, Oral, Combined, Estradiol, Exercise, Female, Follicular Phase, Humans, Menstrual Cycle, Young Adult",
author = "Lisa Umlauff and Peter Weil and Philipp Zimmer and Hackney, {Anthony C} and Wilhelm Bloch and Moritz Schumann",
note = "Copyright {\textcopyright} 2021 National Strength and Conditioning Association.",
year = "2021",
month = apr,
day = "1",
doi = "10.1519/JSC.0000000000003958",
language = "English",
volume = "35",
pages = "894--901",
journal = "Journal of strength and conditioning research / National Strength & Conditioning Association",
issn = "1064-8011",
publisher = "NSCA National Strength and Conditioning Association",
number = "4",

}

RIS

TY - JOUR

T1 - Oral Contraceptives Do Not Affect Physiological Responses to Strength Exercise

AU - Umlauff, Lisa

AU - Weil, Peter

AU - Zimmer, Philipp

AU - Hackney, Anthony C

AU - Bloch, Wilhelm

AU - Schumann, Moritz

N1 - Copyright © 2021 National Strength and Conditioning Association.

PY - 2021/4/1

Y1 - 2021/4/1

N2 - ABSTRACT: Umlauff, L, Weil, P, Zimmer, P, Hackney, AC, Bloch, W, and Schumann, M. Oral contraceptives do not affect physiological responses to strength exercise. J Strength Cond Res 35(4): 894-901, 2021-This study investigated the effect of oral contraceptive (OC) use on acute changes in steroid hormone concentrations and tryptophan (TRP) metabolites in response to strength exercise. Twenty-one women (age: 23 ± 3 years), 8 combined OC users (OC group) and 13 naturally cycling women (menstrual cycle [MC] group), participated. Testing was performed during the pill-free interval for the OC group and the follicular phase for the MC group. Subjects completed an intense strength exercise protocol (4 × 10 repetitions back squat). Blood samples were taken at baseline (T0), post-exercise (T1), and after 24 hours (T2) to determine serum concentrations of cortisol, estradiol, testosterone, TRP, and kynurenine (KYN). Statistical significance was defined as p ≤ 0.05. At T0, the OC group showed higher cortisol (OC: 493.7 ± 47.1 ng·mL-1, MC: 299.1 ± 62.7 ng·mL-1, p < 0.001) and blood lactate (OC: 1.81 ± 0.61 mmol·L-1, MC: 1.06 ± 0.30 mmol·L-1, p = 0.001) and lower estradiol (OC: 31.12 ± 4.24 pg·mL-1, MC: 38.34 ± 7.50 pg·mL-1, p = 0.023) and KYN (OC: 1.15 ± 0.23 µmol·L-1, MC: 1.75 ± 0.50 µmol·L-1, p = 0.005). No significant interactions (group × time, p > 0.05) were found for the hormones and TRP metabolites assessed. Oral contraceptive use did not affect the physiological response of steroid hormones and TRP metabolites to acute strength exercise during the low hormone phase of the contraceptive or MC in healthy young women, even when some baseline concentrations differed between groups. Consequently, these findings provide important implications for practitioners testing heterogeneous groups of female athletes.

AB - ABSTRACT: Umlauff, L, Weil, P, Zimmer, P, Hackney, AC, Bloch, W, and Schumann, M. Oral contraceptives do not affect physiological responses to strength exercise. J Strength Cond Res 35(4): 894-901, 2021-This study investigated the effect of oral contraceptive (OC) use on acute changes in steroid hormone concentrations and tryptophan (TRP) metabolites in response to strength exercise. Twenty-one women (age: 23 ± 3 years), 8 combined OC users (OC group) and 13 naturally cycling women (menstrual cycle [MC] group), participated. Testing was performed during the pill-free interval for the OC group and the follicular phase for the MC group. Subjects completed an intense strength exercise protocol (4 × 10 repetitions back squat). Blood samples were taken at baseline (T0), post-exercise (T1), and after 24 hours (T2) to determine serum concentrations of cortisol, estradiol, testosterone, TRP, and kynurenine (KYN). Statistical significance was defined as p ≤ 0.05. At T0, the OC group showed higher cortisol (OC: 493.7 ± 47.1 ng·mL-1, MC: 299.1 ± 62.7 ng·mL-1, p < 0.001) and blood lactate (OC: 1.81 ± 0.61 mmol·L-1, MC: 1.06 ± 0.30 mmol·L-1, p = 0.001) and lower estradiol (OC: 31.12 ± 4.24 pg·mL-1, MC: 38.34 ± 7.50 pg·mL-1, p = 0.023) and KYN (OC: 1.15 ± 0.23 µmol·L-1, MC: 1.75 ± 0.50 µmol·L-1, p = 0.005). No significant interactions (group × time, p > 0.05) were found for the hormones and TRP metabolites assessed. Oral contraceptive use did not affect the physiological response of steroid hormones and TRP metabolites to acute strength exercise during the low hormone phase of the contraceptive or MC in healthy young women, even when some baseline concentrations differed between groups. Consequently, these findings provide important implications for practitioners testing heterogeneous groups of female athletes.

KW - Adult

KW - Contraceptives, Oral, Combined

KW - Estradiol

KW - Exercise

KW - Female

KW - Follicular Phase

KW - Humans

KW - Menstrual Cycle

KW - Young Adult

U2 - 10.1519/JSC.0000000000003958

DO - 10.1519/JSC.0000000000003958

M3 - Journal articles

C2 - 33555830

VL - 35

SP - 894

EP - 901

JO - Journal of strength and conditioning research / National Strength & Conditioning Association

JF - Journal of strength and conditioning research / National Strength & Conditioning Association

SN - 1064-8011

IS - 4

ER -

ID: 5988085