Polyamines, myosin heavy chains, and collagen specific amino acids after a repeated bout of eccentric exercise

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Polyamines, myosin heavy chains, and collagen specific amino acids after a repeated bout of eccentric exercise. / Behringer, Michael; Montag, Johannes Caspar Konrad; Kilian, Yvonne; Heaton, Phil; Mester, Joachim.

In: Research in sports medicine (Print), Vol. 24, No. 3, 06.07.2016, p. 272-282.

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@article{c1482c9c7540471281e10c82378d437c,
title = "Polyamines, myosin heavy chains, and collagen specific amino acids after a repeated bout of eccentric exercise",
abstract = "We investigated alternatives to commonly used biomarkers of exercise-induced tissue damage. Over 5 days following two bouts of 100 drop-to-vertical jumps (inter-bout rest period of 3 weeks), myosin heavy chain 1, hydroxylysine (HYL), hydroxyproline (HYP), spermine (SPM) and spermine synthase (SMS) were measured in the serum of 10 participants. HYL significantly increased from 5.92 ± 1.49 ng/mL to 6.48 ± 1.47 ng/mL at 24 h. A similar trend was observed for bout 2, but without reaching significance. SPM significantly increased only after bout 1 from 0.96 ± 0.19 ng/mL at pretest to a peak level of 1.12 ± 0.26 ng/mL at 24 h, while B2 increments remained non-significant. Myosin heavy chain 1, HYP and SMS values remained below the detection limit of the applied enzyme-linked immunosorbent assay (ELISA) kit. Though HYL and SM increased after the intervention, both markers showed a large standard deviation (SD) combined with small increments. Therefore, none of the investigated biomarkers provides a meaningful alternative to commonly used damage markers.",
keywords = "Journal Article",
author = "Michael Behringer and Montag, {Johannes Caspar Konrad} and Yvonne Kilian and Phil Heaton and Joachim Mester",
year = "2016",
month = jul,
day = "6",
doi = "10.1080/15438627.2016.1202830",
language = "English",
volume = "24",
pages = "272--282",
journal = "Research in sports medicine (Print)",
issn = "1543-8627",
publisher = "Taylor and Francis Ltd.",
number = "3",

}

RIS

TY - JOUR

T1 - Polyamines, myosin heavy chains, and collagen specific amino acids after a repeated bout of eccentric exercise

AU - Behringer, Michael

AU - Montag, Johannes Caspar Konrad

AU - Kilian, Yvonne

AU - Heaton, Phil

AU - Mester, Joachim

PY - 2016/7/6

Y1 - 2016/7/6

N2 - We investigated alternatives to commonly used biomarkers of exercise-induced tissue damage. Over 5 days following two bouts of 100 drop-to-vertical jumps (inter-bout rest period of 3 weeks), myosin heavy chain 1, hydroxylysine (HYL), hydroxyproline (HYP), spermine (SPM) and spermine synthase (SMS) were measured in the serum of 10 participants. HYL significantly increased from 5.92 ± 1.49 ng/mL to 6.48 ± 1.47 ng/mL at 24 h. A similar trend was observed for bout 2, but without reaching significance. SPM significantly increased only after bout 1 from 0.96 ± 0.19 ng/mL at pretest to a peak level of 1.12 ± 0.26 ng/mL at 24 h, while B2 increments remained non-significant. Myosin heavy chain 1, HYP and SMS values remained below the detection limit of the applied enzyme-linked immunosorbent assay (ELISA) kit. Though HYL and SM increased after the intervention, both markers showed a large standard deviation (SD) combined with small increments. Therefore, none of the investigated biomarkers provides a meaningful alternative to commonly used damage markers.

AB - We investigated alternatives to commonly used biomarkers of exercise-induced tissue damage. Over 5 days following two bouts of 100 drop-to-vertical jumps (inter-bout rest period of 3 weeks), myosin heavy chain 1, hydroxylysine (HYL), hydroxyproline (HYP), spermine (SPM) and spermine synthase (SMS) were measured in the serum of 10 participants. HYL significantly increased from 5.92 ± 1.49 ng/mL to 6.48 ± 1.47 ng/mL at 24 h. A similar trend was observed for bout 2, but without reaching significance. SPM significantly increased only after bout 1 from 0.96 ± 0.19 ng/mL at pretest to a peak level of 1.12 ± 0.26 ng/mL at 24 h, while B2 increments remained non-significant. Myosin heavy chain 1, HYP and SMS values remained below the detection limit of the applied enzyme-linked immunosorbent assay (ELISA) kit. Though HYL and SM increased after the intervention, both markers showed a large standard deviation (SD) combined with small increments. Therefore, none of the investigated biomarkers provides a meaningful alternative to commonly used damage markers.

KW - Journal Article

U2 - 10.1080/15438627.2016.1202830

DO - 10.1080/15438627.2016.1202830

M3 - Journal articles

C2 - 27379471

VL - 24

SP - 272

EP - 282

JO - Research in sports medicine (Print)

JF - Research in sports medicine (Print)

SN - 1543-8627

IS - 3

ER -

ID: 2857165