Prehabilitation in patients awaiting elective coronary artery bypass graft surgery - effects on functional capacity and quality of life: a randomized controlled trial

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Prehabilitation in patients awaiting elective coronary artery bypass graft surgery - effects on functional capacity and quality of life : a randomized controlled trial. / Steinmetz, Carolin; Bjarnason-Wehrens, Birna; Baumgarten, Heike et al.

In: Clinical Rehabilitation, Vol. 34, No. 10, 2020, p. 1256-1267.

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@article{d106d6c02ad34dcfbf66e7a76572f058,
title = "Prehabilitation in patients awaiting elective coronary artery bypass graft surgery - effects on functional capacity and quality of life: a randomized controlled trial",
abstract = "OBJECTIVE: To determine the impact of an exercise-based prehabilitation (EBPrehab) program on pre- and postoperative exercise capacity, functional capacity (FC) and quality of life (QoL) in patients awaiting elective coronary artery bypass graft surgery (CABG).DESIGN: A two-group randomized controlled trail.SETTING: Ambulatory prehabilitation.SUBJECTS: Overall 230 preoperative elective CABG-surgery patients were randomly assigned to an intervention (IG, n = 88; n = 27 withdrew after randomization) or control group (CG, n = 115).INTERVENTION: IG: two-week EBPrehab including supervised aerobic exercise. CG: usual care.MAIN MEASURES: At baseline (T1), one day before surgery (T2), at the beginning (T3) and at the end of cardiac rehabilitation (T4) the following measurements were performed: cardiopulmonary exercise test, six-minute walk test (6MWT), Timed-Up-and-Go Test (TUG) and QoL (MacNew questionnaire).RESULTS: A total of 171 patients (IG, n = 81; CG, n = 90) completed the study. During EBPrehab no complications occurred. Preoperatively FC (6MWTIG: 443.0 ± 80.1 m to 493.5 ± 75.5 m, P = 0.003; TUGIG: 6.9 ± 2.0 s to 6.1 ± 1.8 s, P = 0.018) and QoL (IG: 5.1 ± 0.9 to 5.4 ± 0.9, P < 0.001) improved significantly more in IG compared to CG. Similar effects were observed postoperatively in FC (6MWDIG: Δ-64.7 m, pT1-T3 = 0.013; Δ+47.2 m, pT1-T4 < 0.001; TUGIG: Δ+1.4 s, pT1-T3 = 0.003).CONCLUSIONS: A short-term EBPrehab is effective to improve perioperative FC and preoperative QoL in patients with stable coronary artery disease awaiting CABG-surgery.ID: NCT04111744 (www.ClinicalTrials.gov; Preoperative Exercise Training for Patients Undergoing Coronary Artery Bypass Graft Surgery- A Prospective Randomized Trial).",
keywords = "Aged, Coronary Artery Bypass/rehabilitation, Coronary Artery Disease/rehabilitation, Elective Surgical Procedures, Exercise Test, Exercise Tolerance, Female, Humans, Male, Middle Aged, Postural Balance, Preoperative Exercise, Prospective Studies, Quality of Life, Surveys and Questionnaires, Time and Motion Studies",
author = "Carolin Steinmetz and Birna Bjarnason-Wehrens and Heike Baumgarten and Thomas Walther and Thomas Mengden and Claudia Walther",
year = "2020",
doi = "10.1177/0269215520933950",
language = "English",
volume = "34",
pages = "1256--1267",
journal = "Clinical Rehabilitation",
issn = "0269-2155",
publisher = "SAGE Publications Ltd",
number = "10",

}

RIS

TY - JOUR

T1 - Prehabilitation in patients awaiting elective coronary artery bypass graft surgery - effects on functional capacity and quality of life

T2 - a randomized controlled trial

AU - Steinmetz, Carolin

AU - Bjarnason-Wehrens, Birna

AU - Baumgarten, Heike

AU - Walther, Thomas

AU - Mengden, Thomas

AU - Walther, Claudia

PY - 2020

Y1 - 2020

N2 - OBJECTIVE: To determine the impact of an exercise-based prehabilitation (EBPrehab) program on pre- and postoperative exercise capacity, functional capacity (FC) and quality of life (QoL) in patients awaiting elective coronary artery bypass graft surgery (CABG).DESIGN: A two-group randomized controlled trail.SETTING: Ambulatory prehabilitation.SUBJECTS: Overall 230 preoperative elective CABG-surgery patients were randomly assigned to an intervention (IG, n = 88; n = 27 withdrew after randomization) or control group (CG, n = 115).INTERVENTION: IG: two-week EBPrehab including supervised aerobic exercise. CG: usual care.MAIN MEASURES: At baseline (T1), one day before surgery (T2), at the beginning (T3) and at the end of cardiac rehabilitation (T4) the following measurements were performed: cardiopulmonary exercise test, six-minute walk test (6MWT), Timed-Up-and-Go Test (TUG) and QoL (MacNew questionnaire).RESULTS: A total of 171 patients (IG, n = 81; CG, n = 90) completed the study. During EBPrehab no complications occurred. Preoperatively FC (6MWTIG: 443.0 ± 80.1 m to 493.5 ± 75.5 m, P = 0.003; TUGIG: 6.9 ± 2.0 s to 6.1 ± 1.8 s, P = 0.018) and QoL (IG: 5.1 ± 0.9 to 5.4 ± 0.9, P < 0.001) improved significantly more in IG compared to CG. Similar effects were observed postoperatively in FC (6MWDIG: Δ-64.7 m, pT1-T3 = 0.013; Δ+47.2 m, pT1-T4 < 0.001; TUGIG: Δ+1.4 s, pT1-T3 = 0.003).CONCLUSIONS: A short-term EBPrehab is effective to improve perioperative FC and preoperative QoL in patients with stable coronary artery disease awaiting CABG-surgery.ID: NCT04111744 (www.ClinicalTrials.gov; Preoperative Exercise Training for Patients Undergoing Coronary Artery Bypass Graft Surgery- A Prospective Randomized Trial).

AB - OBJECTIVE: To determine the impact of an exercise-based prehabilitation (EBPrehab) program on pre- and postoperative exercise capacity, functional capacity (FC) and quality of life (QoL) in patients awaiting elective coronary artery bypass graft surgery (CABG).DESIGN: A two-group randomized controlled trail.SETTING: Ambulatory prehabilitation.SUBJECTS: Overall 230 preoperative elective CABG-surgery patients were randomly assigned to an intervention (IG, n = 88; n = 27 withdrew after randomization) or control group (CG, n = 115).INTERVENTION: IG: two-week EBPrehab including supervised aerobic exercise. CG: usual care.MAIN MEASURES: At baseline (T1), one day before surgery (T2), at the beginning (T3) and at the end of cardiac rehabilitation (T4) the following measurements were performed: cardiopulmonary exercise test, six-minute walk test (6MWT), Timed-Up-and-Go Test (TUG) and QoL (MacNew questionnaire).RESULTS: A total of 171 patients (IG, n = 81; CG, n = 90) completed the study. During EBPrehab no complications occurred. Preoperatively FC (6MWTIG: 443.0 ± 80.1 m to 493.5 ± 75.5 m, P = 0.003; TUGIG: 6.9 ± 2.0 s to 6.1 ± 1.8 s, P = 0.018) and QoL (IG: 5.1 ± 0.9 to 5.4 ± 0.9, P < 0.001) improved significantly more in IG compared to CG. Similar effects were observed postoperatively in FC (6MWDIG: Δ-64.7 m, pT1-T3 = 0.013; Δ+47.2 m, pT1-T4 < 0.001; TUGIG: Δ+1.4 s, pT1-T3 = 0.003).CONCLUSIONS: A short-term EBPrehab is effective to improve perioperative FC and preoperative QoL in patients with stable coronary artery disease awaiting CABG-surgery.ID: NCT04111744 (www.ClinicalTrials.gov; Preoperative Exercise Training for Patients Undergoing Coronary Artery Bypass Graft Surgery- A Prospective Randomized Trial).

KW - Aged

KW - Coronary Artery Bypass/rehabilitation

KW - Coronary Artery Disease/rehabilitation

KW - Elective Surgical Procedures

KW - Exercise Test

KW - Exercise Tolerance

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Postural Balance

KW - Preoperative Exercise

KW - Prospective Studies

KW - Quality of Life

KW - Surveys and Questionnaires

KW - Time and Motion Studies

U2 - 10.1177/0269215520933950

DO - 10.1177/0269215520933950

M3 - Journal articles

C2 - 32546065

VL - 34

SP - 1256

EP - 1267

JO - Clinical Rehabilitation

JF - Clinical Rehabilitation

SN - 0269-2155

IS - 10

ER -

ID: 6042210